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Royan Institute

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The main activities and researches of Royan institute for Animal Biotechnology:
  • Production of the first cloned sheep in Iran
  • Production of the first cloned cow in Iran
  • Production of the first cloned goat in Iran
  • Production of the first transgenic goat carrying human tPA gene in its genome
  • Production of the first IVF cow, sheep and goat
  • Establishment of novel sperm selection procedures
  • Clinical trials for novel sperm selection procedures
  • Establishment of the genomic bank for local endangered species
  • Publications of book and papers in international and national journals in andrology, stem cell, and cloning
  • Establishment of the International Journal of Fertility and Sterility
  • Isolation of OCT-4 promoter for the control of EGFP gene in an indicator plasmid
  • Construction of a more efficient variant of TPA termed tenctoplase
  • Cloning of PEP and PPAR gamma cDNAs
  • Investigating the role of PEP and PPAR gamma for the first time in embryonic stem cell
  • Cell transplantation on animal with spinal cord injury
  • Use of co culture models to study differentiation under controlled conditions for investigation of early developmental events in mammals
  • Introducing simple, fast, inexpensive, and efficient methods for production of both homogenous and purified cells such as SC (Schwan cells) and SHED (Stem cell from human exfoliated Deciduce tooth)
  • Use of scaffold materials as a matrix for tissue engineering
  • Drug screening and toxicity studies by embryonic and adult stem cell culture
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Most important research of Royan Institute for Animal Biotechnology in 2009:

  • Production of the first transgenic goat carrying human tPA gene in its genome
  • Novel sperm selection procedure for ICSI


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