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Nominees and Winners of 9th Royan international research award have been announced after final scoring

Stem cell group:

1. Su-Chun  Zhang (USA), Human embryonic stem cells as a tool of discovery
2. Yusuke Furukawa (Japan), E2F-6 suppresses growth-associated apoptosis of human hematopoietic?stem/progenitor cells by counteracting proapoptotic activity of E2F-1
3. Xin-fu Zhou (Australia), Isolation and characterization of neural crest stem cells from adult sensory ganglia
4. Karsten Hemmrich (Germany), Plasticity of human adipose stem cells to perform adipogenic and endothelial differentiation
5. Paul Thomas (), Survival and differentiation of pituitary colony forming cells in vivo
6. Yoon Ha (Korea), Complete Spinal Cord Injury Treatment Using Autologous Bone Marrow Cell Transplantation and Bone Marrow Stimulation with Granulocyte Macrophage-Colony Stimulating Factor: Phase I/II Clinical Trial
7. Alice pebay  (Australia),  Signalling pathways involved in human embryonic stem cell maintenance
8. Johnny Huard (USA), Malignant Transformation of Multipotent Muscle-Derived Cells by Concurrent Differentiation Signals
9. Louache Fawzia (France),  Identification of CXCR4 as a new nitric oxide regulated gene in human CD34+ cells
10. Fardin Fathi (Iran),  Characterizing Endothelial Cells Derived From the Murine Embryonic Stem Cell Line CCE

Gynecology Group:

1. Federico Prefumo (Italy), Uterine Doppler investigations and trophoblast biology in early pregnancy
2. Pasquale Florio (Italy),  Role of activin A and urocortins in endometriosis: phisio-pathological implications
3. Antonio La Marca  (Italy), Anti-Müllerian hormone measurement on any day of the menstrual cycle strongly predicts ovarian response in assisted reproductive technology.
4. Kok-min Seow (Taiwan),  Adipocyte resistin mRNA levels are downregulated by laparoscopic ovarian electrocautery in both obese and lean women with polycystic ovary syndrome
5. Lalitkumar Parameswaran Grace (Sweden), In vitro human embryo implantation on a receptive endometrial construct – Cell biology and its progesterone regulation
6. Giovanni Ruvolo (Italy), Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures
7. Smita Mahale  (India), Structural, functional and molecular aspects of follicle stimulating hormone receptor: applications in designing receptor targets and management of female infertility
8. Sylvia Mechsner  (Germany), GAP-43-positive sensory nerve fibers accompanied by immature vessels are located in or near peritoneal endometriotic lesions

Andrology Group:

1. Maria Dufau (USA), Gonadotropin-regulated testicular helicase (GRTH/DDX25): a master post-transcriptional regulator of spermatogenesis
2. Piotr Pierzynski (UK), Effect of atosiban on rabbit embryo development and human sperm motility
3. Fabio Pasqualotto (Brazil), Testicular apoptosis in infertile men with varicocele and the relationship with hpv infection
4. Tsutomu Ogata  (Japan), Haplotype analysis of the estrogen receptor alpha gene in male genital and reproductive abnormalities
5. Colin McKerlie  (Canada), Effects of cryopreservation on sperm quality, nuclear DNA integrity, in vitro fertilization, and in vitro embryo development in the mouse
6. Carsten Obel (Denmark), Psychological distress during early gestation and offspring sex ratio.
7. Fabio Pasqualotto (Brazil), Relationship between seminal antioxidants and the presence of papillomavirus infection
8. Evangelos Alexopoulos (Greece), Secondary sex ratio in Greece: evidence of an influence by father’s occupational exposure
9. Ruben Motrich  (Argentina), Effect of tamoxifen treatment on the semen quality and fertility of the male rat
10. Wang Ru (China), A frequent Y chromosome b2/b3 subdeletion shows strong association with male infertility in Han-Chinese population  

Embryology Group:

1. Ana Sofia Lopes  (Denmark), Investigation of respiration of individual bovine embryos produced in vivo and in vitro and correlation with viability following transfer
2. Leen Vanhoutte (Belgium), Nuclear and cytoplasmic maturation of in vitro matured human oocytes after temporary nuclear arrest by phosphodiesterase 3-inhibitor
3. Maria Dufau (USA), Gonadotropin-regulated testicular helicase (GRTH/DDX25): a master post-transcriptional regulator of spermatogenesis
4. Hubert Smeets (Netherlands), mtDNA point mutations are present at various levels of heteroplasmy in human oocytes
5. Ya Ni (China), Acrosome reaction induced by recombinant human zona pellucida 3 peptides rhuZP3a22~176 and rhuZP3b177~348 and their mechanism
6. Sumio Ishijima (Japan), Digital image analysis of the flagellar beat of activated and hyperactivated suncus spermatozoa
7. Piotr Pierzynski (UK), Effect of atosiban on rabbit embryo development and human sperm motility
8. Paolo Rinaudo (USA), Effect of in-vitro fertilization (IVF) on gene expression and development of mouse preimplantation embryos
9. Lalitkumar Parameswaran Grace (Sweden), Invitro human embryo implantation on a receptive endometrial construct – Cell biology and its progesterone regulation
10. Takashi Yamashiro (Japan)
 Wnt10a regulates dentin sialophosphoprotein mRNA expression and possibly links odontoblast differentiation and tooth morphogenesis.    

 Genetic Group:

1. Smita Mahale (India), Structural, Functional and Molecular Aspects of Follicle Stimulating Hormone Receptor: Applications in Designing Receptor Targets and Management of Female Infertility
2. Krina Zondervan (UK), Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15
3. Jonas Frisen (Sweden), High-throughput identification of genes promoting neuron formation and lineage choice in mouse embryonic stem cells
4. Yan Li (China),  Association of three Single Nucleotide Polymorphisms of the E-cadherin Gene with Endometriosis in a Chinese population
5. Masayuki Shimada (Japan), Synaptosomal-Associated Protein 25 Gene Expression Is Hormonally Regulated during Ovulation and Is Involved in Cytokine/Chemokine Exocytosis from Granulosa Cells
6. Maria Dufau  (USA), Gonadotropin-regulated testicular helicase (GRTH/DDX25): a master post-transcriptional regulator of spermatogenesis
7. Mona Bungum (Denmark), Sperm DNA integrity assessment in prediction of outcome of assisted reproduction
8. Ali Fathi (Iran), The molecular mechanisms controlling embryonic stem cells (ESCs) proliferation and differentiation
9. Michele Boiani (Germany), Chromosome stability differs in cloned mouse embryos and derivative ES cells: implications for therapeutic cloning
10. Anjali  Shiras (India), Genomic instability drives transformation of neural stem cells to cancer stem cells.
    

 

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