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The main activities and researches of Royan institute for Animal Biotechnology:
- Production of the first cloned sheep in Iran
- Production of the first cloned cow in Iran
- Production of the first cloned goat in Iran
- Production of the first transgenic goat carrying human tPA gene in its genome
- Production of the first IVF cow, sheep and goat
- Establishment of novel sperm selection procedures
- Clinical trials for novel sperm selection procedures
- Establishment of the genomic bank for local endangered species
- Publications of book and papers in international and national journals in andrology, stem cell, and cloning
- Establishment of the International Journal of Fertility and Sterility
- Isolation of OCT-4 promoter for the control of EGFP gene in an indicator plasmid
- Construction of a more efficient variant of TPA termed tenctoplase
- Cloning of PEP and PPAR gamma cDNAs
- Investigating the role of PEP and PPAR gamma for the first time in embryonic stem cell
- Cell transplantation on animal with spinal cord injury
- Use of co culture models to study differentiation under controlled conditions for investigation of early developmental events in mammals
- Introducing simple, fast, inexpensive, and efficient methods for production of both homogenous and purified cells such as SC (Schwan cells) and SHED (Stem cell from human exfoliated Deciduce tooth)
- Use of scaffold materials as a matrix for tissue engineering
- Drug screening and toxicity studies by embryonic and adult stem cell culture
 Most important research of Royan Institute for Animal Biotechnology in 2009:
- Production of the first transgenic goat carrying human tPA gene in its genome
- Novel sperm selection procedure for ICSI
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